potassium citrate vs potassium chloride vs potassium gluconate

Bottom Line Potassium Gluconate vs Potassium Chloride The main differences between the two medicines are that the KCI is given if there are low levels of both chloride and potassium in the blood, while KG is given to patients as a supplement if he has a healthy chloride level. The sources cited below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government data. Epub 2013 May 29. Dietary potassium regulates vascular calcification and arterial stiffness. Chronic hypokalemia is associated with hypertension and kidney stone formation (see Disease Prevention and Disease Treatment). (PubMed), 35. Adler AJ, Taylor F, Martin N, Gottlieb S, Taylor RS, Ebrahim S. Reduced dietary salt for the prevention of cardiovascular disease. Each replenishes the bodys potassium but the type you should use is determined by underlying physical conditions. Which is extra strength? Its formula is: c6h11ko7. The most serious adverse reaction to potassium supplementation is hyperkalemia, yet is rare in subjects with normal kidney function (see Toxicity). Its used to replenish low blood potassium, to maintain normal levels, or to avoid potassium depletion during specific drug therapies and certain diseases. Both potassium citrate and potassium gluconate may be used as food additives or supplements, but they have some slightly different applications. Newberry SJ, Chung M, Anderson CAM, et al. The usual dose is 1 to 3 mEq per kg (0.45 to 1.36 mEq per pound) of body weight taken in smaller doses during the day. Corvallis, Oregon 97331, phone: 541-737-5075 | fax: 541-737-5077 Linus Pauling Institute 1998;339(7):451-458. (PubMed), 24. Data sources include IBM Watson Micromedex (updated 2 Apr 2023), Cerner Multum (updated 17 Apr 2023), ASHP (updated 10 Apr 2023) and others. Potassium/Professional Monograph/Nutrient Depletion. Adults and teenagers20 milliequivalents (mEq) diluted in 2 tablespoonfuls or more of cold water or juice, taken two to four times a day. Neither should be taken until a medical evaluation and blood tests have been completed. Theyre also not available in the same dosage forms. Potassium citrate acts as a diuretic (making you pee more), and is used to manage, prevent or treat conditions such as: Potassium gluconate may be used to manage, prevent or treat low potassium levels (hypokalemia). This supplement is also known as the D-gluconic acid potassium salt or potassium D-gluconate. It is used when your urine is too acidic. Both potassium citrate and potassium gluconate may be used as food additives or supplements, but they have some slightly different applications. Moreover, taking potassium D-gluconate might help support the health of the bones since this mineral makes up a small component of the bone tissue, forming the compound in the bones responsible for bone density. Take this medicine only as directed by your doctor. J Am Heart Assoc. Trinchieri A, Zanetti G, Curro A, Lizzano R. Effect of potential renal acid load of foods on calcium metabolism of renal calcium stone formers. However, potassium gluconate contains less elemental Potassium citrate is an alkalizing agent. Do not chew or suck on the tablet. Dietary magnesium and potassium intakes and circulating magnesium are associated with heel bone ultrasound attenuation and osteoporotic fracture risk in the EPIC-Norfolk cohort study. In this study, all participants received daily supplements of calcium carbonate (500 mg/day) and vitamin D (10 g/day). However, most people will not take more than 100 mEq a day. https://www.ncbi.nlm.nih.gov/pubmed/27413123, https://www.researchgate.net/publication/305343197, https://journals.lww.com/jbisrir/Fulltext/2011/09481/, Histrionic vs Borderline Personality Disorder Differences. However, most people will not take more than 100 mEq a day. It metabolizes quickly to reduce the acid level in urine and decrease the formation of kidney stones. Potassium is a normal component of a regular, well rounded diet and is contained in many foods such as meats, fruits and vegetables. The concentration differences between potassium and sodium across cell membranes create an electrochemical gradient known as the membrane potential. PMC Potassium electrolyte helps the muscles to contract or relax by controlling the transport Furthermore, this mineral is an important health nutrient that is good for reducing the risk of kidney stones, lowering blood pressure, reducing the risk of stroke, and increasing bone-beneficial calcium. Available at: https://naturalmedicines.therapeuticresearch.com. Dr. Brian has been practicing pharmacy for over 13 years and has wide-ranging experiences in many different areas of the profession. Dion M, Ankawi G, Chew B, Paterson R, Sultan N, Hoddinott P, Razvi H. Can Urol Assoc J. The usual dose is 1 to 3 mEq of potassium per kilogram (kg) (0.45 to 1.36 mEq per pound) of body weight taken in smaller doses during the day. Forty-five percent of US adults have hypertension (blood pressure levels 130/80 mm Hg) (33). However, most people will not take more than 100 mEq a day. You may hyperlink to this website but must include the following statement: "This link leads to a website provided by the Linus Pauling Institute at Oregon State University. A 2014 meta-analysis of 17 randomized controlled trials that examined the effect of the DASH diet compared to a control diet in a total of 2,561 adults found overall reductions in systolic and diastolic blood pressure by 6.7 mm Hg and 3.5 mm Hg, respectively (39). Epub 2018 Nov 26. Epub 2016 Nov 10. Abnormally elevated serum potassium concentrations are referred to as hyperkalemia. Her work has been published in "Prevention," "Nurseweek" and "Senior Life." Am J Med Sci. Do not double doses. The solution should be well mixed into water or juice. Several prospective cohort studies have also found an inverse association between potassium intake and risk of stroke. Video chat with a U.S. board-certified doctor 24/7 in less than one minute for common issues such as: colds and coughs, stomach symptoms, bladder infections, rashes, and more. Increasing potassium intake to recommended levels (see Adequate Intake) by consuming a diet rich in fruit and vegetables can help lower blood pressure and may have additional benefits to health (see the article on Fruit and Vegetables). Your doctor may change the dose if needed. A low potassium intake may be one factor which leads to the WebDietary source Of the major minerals, magnesium ranks sixth (Ca 2+ > P > K + > Na + > Cl-> Mg 2+) in overall abundance in the body. This is especially important if you are also taking both diuretics (water pills) and digitalis medicines for your heart. Drug information provided by: Merative, Micromedex. Rashes may occasionally occur. What's more appropriate for hypokalemia or hypokalemic periodic paralysis? (PubMed), 38. Various mechanisms explain how certain medications can lead to potassium depletion. Taking potassium with meals or taking a microencapsulated form of potassium may reduce gastrointestinal side effects (50). Epub 2022 May 8. Please enable it to take advantage of the complete set of features! Get answers from Nephrologists and top U.S. doctors, Our doctors evaluate, diagnose, prescribe, order lab tests, and recommend follow-up care. US Department of Agriculture, Agricultural Research Service. Potassium gluconate is advised as an adjunct in treatment of hypertension, cardiac and metabolic disorders. One of the preferred forms of potassium for a ketogenic diet would be Potassium CHLORIDE. Qualitative analysis of anions. Clausen T. Quantification of Na+,K+ pumps and their transport rate in skeletal muscle: functional significance. 1994;23(2):359-377. Estimated 24-hour urinary sodium and potassium excretion in US adults. However, most people will not take more than 100 mEq a day. Unauthorized use of these marks is strictly prohibited. Thanks. Potassium chloride and potassium citrate have similar names, so they should treat the same conditions, right? Not quite. While they are both supplements that contain potassium, the two actually have different uses, side effects and dosages, and cannot be substituted for each other.Potassium chloride is a mineral used to replenish potassium within our body. Fact Sheet for Consumers. We comply with the HONcode standard for trustworthy health information. Because of the potential for serious side effects, one should seek medical advice before deciding to use a potassium supplement (see Safety ). (PubMed), 32. WebPotassium Citrate and Potassium Gluconate Versus Potassium Chloride: Experimental Evaluation of Relative Intestinal Toxicity Scott J. Boley, MD ; Leon Schultz, MD ; Solomon Schwartz, MD ; et al Armand Katz, MD ; Arthur C. Allen, MD It is responsible for transmission of electrical impulses in the heart which control heart beat. WebDr. Am J Clin Nutr. In: Stipanuk M, ed. Unlike 24-hour dietary recalls, 24-hour urine collections provide accurate estimates of dietary intakes of sodium and potassium (36). Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. 2015 Jul 7;87(2):105-20. doi: 10.4081/aiua.2015.2.105. Clin Nutr. WebPotassium chloride tastes similar to sodium chloride (table salt), potassium citrate is tart, potassium gluconate is basically tasteless. Victoria J. Drake, Ph.D. Correction of hypocitraturia and prevention of stone formation by combined thiazide and potassium citrate therapy in thiazide-unresponsive hypercalciuric nephrolithiasis. Jane Higdon, Ph.D. Common serious side effects of taking these supplements may include: Serious side effects (very rare) may include: This type of supplement can also cause narrowing of the small intestine from healed ulcers and perforation or bleeding of the small intestine or stomach from ulcers. Potassium chloride is used as a supplement to raise potassium levels in your body. Overall, whether consuming potassium-rich fruit and vegetables can influence bone health and help lower the risk of osteoporosis remains uncertain (see also the article on Fruit and Vegetables). Adults and teenagers20 mEq mixed in 2 tablespoonfuls or more of cold water or juice taken two to four times a day. It is important to discuss your options with your doctor as there are a variety of factors that need to be taken into consideration in regards to regaining normal potassium levels. The presence of potassium is also required for the activity of pyruvate kinase, an important enzyme in carbohydrate metabolism (5). However, most people will not take more than 100 mEq a day. Potassium chloride is 52% elemental potassium by mass while potassium gluconate is only 16.7% elemental potassium by mass. It metabolizes quickly to reduce the acid level in urine and decrease the formation of stones... Reaction to potassium supplementation is hyperkalemia, yet is rare in subjects with kidney! Consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government data of may. Is also known as the membrane potential books and newsletters from Mayo Clinic Press corvallis, Oregon,! Below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government.! Adults and teenagers20 mEq mixed in 2 tablespoonfuls or more of cold water or juice two. 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Her work has been published in `` Prevention, '' `` Nurseweek '' and `` Senior Life. over potassium citrate vs potassium chloride vs potassium gluconate... Consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, government! Should use is determined by underlying physical conditions this medicine only as directed by your doctor activity pyruvate! Taking both diuretics ( water pills ) and digitalis medicines for your heart chronic is... Excretion in US adults, but they have some slightly different applications '' and `` Life... Is hyperkalemia, yet is rare in subjects with normal kidney function ( see Toxicity ) both potassium citrate potassium.

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